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How We Can Do Better Drug Discovery | Jack Scannell

The DeSci Podcast

CHAPTER

Antibiotic Drug Discovery

The early success of antibiotics pharmacology has kind of colored the way that we approach drug discovery in general especially in the oncology field. A lot of decision theoretic math circa 2016 led to the view that model quality beats quantity right i.e. it's better to test a small number of therapeutic candidates in a really good model than a very large number of therapeutic candidate selected from the same universe for label identity. The answer drops out of decision theory if you look at the trade-off between quality and quantity around antimicrobials. We just need to solve the incentive and financial problems in antibiotic drug discovery.

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