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Journal Review in Surgical Oncology: Gastrointestinal Stromal Tumors (GISTs)

Behind The Knife: The Surgery Podcast

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Efficacy of Different Durations of Matinib Treatment for Gastrointestinal Stromal Tumors

This chapter explores various studies on the effectiveness of matinib treatment for gastrointestinal stromal tumors, focusing on different durations of treatment and their impact on recurrence-free survival and overall survival rates. Results from phase three trials and adjuvant treatment trials are discussed, highlighting the benefits, drawbacks, and considerations for optimal duration of therapy, especially for GISTs with mutations of exon 11. Variations in data interpretation between US and European guidelines are also addressed.

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