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#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
DNA Cutting Enzymes
Our DNA has a DNA repair mechanism, where if a region of the genome gets randomly cut, you will basically scan the genome for anything that matches and sort of use it by homology. So this is called homologous-based repair. All you have to do is the cutting. And you don't have to do the fixing. Because it's already built in. That's exactly right. But the fixing can be co-opted by throwing in a bunch of homologous segments that instead of having your dad's version, have whatever other version you'd like to use.
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