Nevita Clax vs Ruxolietin

Vanettoclax did not really work very well for patients with post mpn ml that were given vanettoclax from different studies. The next drug which is telabresib a bet inhibitor right so bet arbromodomaine inhibitor it's being tested in the same setting as the nevita clax frontline setting. A monoclon antibody that would target specifically mutant caloriticalin and just to perhaps quickly briefly repeat that would be genetic mutation about 30% of MF and ETP patients have.