Dr. Morgan Soffler, a Pulmonologist and ICU intensivist at Beth Israel Deaconess Medical Center (BIDMC), and an Assistant Professor at Harvard Medical School, discusses a case of a patient with hypoxia in the setting of acute respiratory distress with RTL host, Dr. Navin Kumar. Dr. Soffler begins with a broad differential and provides a framework of timing, tempo, and medical history, along with labs and imaging, to sift through the myriad causes of hypoxia. Together, they walk through different forms of respiratory support and when to escalate this support for patients on the wards.