Using Crisper Cassonine to Cut D and a in a Chromozome

base editing and prim atitin share in common that they don't make douglastrands, dana cuts. For the efficient autos out there, they nick the dana. And prime edidine either don't cut d an a at all, or nick dna. Depending on which base editor you are using, prime editing makes at least one nick in the dna. Both technologies are designed to minimize the formation of stranded braks.