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Prophylactic Antibiotics in Severe Alcohol-Related Hepatitis, Autotaxin Inhibitor Ziritaxestat for Idiopathic Pulmonary Fibrosis, Review of Cirrhosis, and more

JAMA Editors' Summary

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Introduction

The benefits of prophylactic antibiotics for hospitalized patients with severe alcohol-related hepatitis are unclear. Infection rates were significantly lower in the Moxacillin-Clavulinate group, but there were no differences in the incidence of a paterino syndrome or improvements in liver function scores below predefined thresholds. Doctors U.N. Forest and William Burnell recommend overlapping antibiotic treatment with subsequent corticosteroid therapy after treatment of baseline infection.

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