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The Sleep Series: H1 Antagonists (Trazodone, Benadryl, Doxepin)

PsychRounds: The Psychiatry Podcast

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Exploring H1 Antagonists for Insomnia Treatment

This chapter discusses the use of various H1 antagonists like trazodone, mirtazapine, and diphenhydramine in treating insomnia. It highlights potential side effects, optimal dosing strategies, and the careful prescribing practices needed due to the lack of FDA approval for most of these medications.

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