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Benefits & Risks of Peptide Therapeutics for Physical & Mental Health

Huberman Lab

Peptides and Growth Hormone in Tissue Repair and Metabolism

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The chapter explores the roles of TB-500 and BPC157 peptides in tissue repair and angiogenesis, highlighting their effects on rejuvenation. It discusses how growth hormone impacts metabolism and muscle growth, emphasizing the decline in growth hormone levels with age and the relationship with IGF-1. Additionally, the chapter delves into the development and usage of peptide therapeutics like sermorelin, tesamorelin, and CJC1295 for promoting growth hormone release and their potential benefits and risks.

In this episode, I explain the major categories and types of peptides currently in use for therapeutic purposes. I discuss peptides for improving tissue rejuvenation and repair, promoting longevity, improving muscle growth and fat loss, and boosting mood, vitality, and libido. I explain the biology of how these peptides work and both their potential benefits and risks. I also discuss peptide sourcing, dosages, cycling, routes of administration, and how peptides work in combination.

This episode will help you better understand the rapidly expanding landscape of peptide therapeutics and how to evaluate if specific peptides might be advantageous towards achieving your physical or mental health goals.

For show notes, including referenced articles and additional resources, please visit hubermanlab.com.

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Thank you to our sponsors

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Levels: https://levels.link/huberman

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LMNT: https://drinklmnt.com/huberman

Momentous: https://livemomentous.com/huberman

Timestamps

(00:00:00) Peptides

(00:03:20) Sponsors: Mateina, Levels & Joovv

(00:07:44) What is a Peptide?

(00:12:06) Peptide Sourcing, Lipopolysaccharide (LPS)

(00:14:48) Rejuvenation & Tissue Repair: BPC-157, Angiogenesis

(00:21:50) BPC-157 & Tissue Injury; Mode of Delivery

(00:27:53) BPC-157: Safety, Doses, Cycling, Tumor Risk

(00:35:16) Sponsor: AG1

(00:36:43) Tissue Repair: Thymosin Beta-4, TB-500

(00:40:49) Growth & Metabolism: Growth Hormone, IGF-1, Risks

(00:45:25) Secretagogues, Sermorelin, Tesamorelin, CJC-1295

(00:52:21) Sponsor: LMNT

(00:53:44) Ipamorelin, Hexarelin, GHRP-3, MK-677; Risks & Timing

(00:58:69) Peptides for Growth Hormone & IGF-1, Risk; Combinations & Dosing

(01:06:12) Longevity: Thymosin Beta-4, Epitalon (Epithalon)

(01:12:09) Vitality: Melanotan, PT-141 (Vyleesi), Risks

(01:17:21) Vitality: Kisspeptin

(01:21:46) Peptides, Potential Benefits, Side-Effects & Risks

(01:24:19) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter

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