
Penicillin
In Our Time
The History of Penicillin
Fleming observed that if penicillin wasn't given for long enough, the bacteria would survive. This was what led to the statement he made in his Nobel Prize winning speech. Chemists were so good and we now had the structure of penicillin by the mid-late 1940s. That allowed chemists to do with the blood cells,. What they did was to add bits to it to start making it less susceptible to things like penicillinases. And this led to a wave of new penicillins, and in fact it led to another group of beta-lactins called Kefelasporin mold. So there was a lot of screening of soils for natural
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