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IMMUNOLOGY2023: Day 2

The Immunology Podcast

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The Effects of Bacteria on Depression in Mice

There's this receptor called the aryl hydrocarbon receptor, which is a tryptophan receptor. It modulates the depressive response in mice and when IBD disrupts this pathway to lead in that's part of what causes the board to press state for treatment. And then other work I've seen even recently in another conference showed that it's transmissible. If you take depressed stool from ulcerative colitis patients and put it into mice or rats, they develop anxiety and depression due to decrease aryl Hydrocarbon receptor activation. Wow. Gosh, your your bacteria are giving you depression. All right. Talking about bacteria, not depression. That's the one.

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