
Shai Carmi: Polygenic risk scores & embryo screening — #5
Manifold
Sciophenia - What Should Be the Risk of an Individual Based on the Polygin Score?
The polyginc resscores that we have right now, the in technical terms, they explain about seven % of the liability, of the variance in liability of the disease. The children of an individual whisky toprania have probability about ten times a higher to become affected compared to random individuals. And what we showd is that the relative risk reduction, it still remains,. i think itit rema corically from the numbers we reported, i think it's a little bit less, maybe not 50%, may be closer to forty%. But itistill quite high on the absolute scale.
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