Laboratory Evidence for the Mechanism

#196

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Melissa and Jam explore the fascinating chemistry behind self tanners. They take listeners on a journey from the discovery of the key sugar in self tanners in the 1960s by Dr. Eva Wittgenstein to the present-day scientific understanding. The episode delves into the Maillard reactions, typically known for browning food, explaining in simple terms how similar reactions color the skin when self tanners are used. Additionally, the hosts discuss the molecular structure of carbohydrates, the generation of free radicals, and the temporary UV sensitivity following self-tanner application. Interactive elements like pop quizzes and listener shout-outs keep the discussion engaging and educational, while also touching on recent studies and encouraging community support. The episode is a blend of fun facts, thorough biochemistry, and practical advice for achieving a safe, sun-kissed look.

00:00 Introduction to Tanning and Self-Tanners
00:41 The Chemistry Behind Self-Tanners
03:14 History and Discovery of Self-Tanners
04:34 The Maillard Reaction Explained
13:17 Debate on the Maillard Reaction in Self-Tanners
24:40 Application and Effects of Self-Tanners
28:15 The Importance of Sunscreen
28:55 Fun Facts About Tanning
30:06 Pop Quiz Time!
31:15 Rewards and Treats
31:57 Dr. Pepper Shake Discussion
34:22 Quiz Results and Reflections
41:11 Listener Questions and Bonus Episode Tease
42:22 Merchandise Shoutout and Closing Remarks

1. https://pubs.acs.org/doi/10.1021/acsomega.2c06124
2. https://pubsapp.acs.org/cen/whatstuff/stuff/7824scit2.html
3. https://www.compoundchem.com/2014/08/07/faketan/
4. https://cen.acs.org/articles/96/i4/Whats-sunless-tanner-and-how-does-it-impart-that-faux-glow.html
5. https://www.sciencedirect.com/science/article/abs/pii/S0143720822003709
6. Garrett & Grisham’s Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

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