The Pros and Cons of TNT for Locally Advanced Rectal Cancer

The TNT arm demonstrated a decreased rate of treatment-related failure compared to the standard and mainly due to fewer distant metastatic disease. This approach doubled the path complete response from 28% from 14, sorry, to 28%. And so I think that's the number that really sticks with me that, you know, improvement in the path full response. So this is a really interesting study design. It was not sort of head to head. It was just a power to select, which is the better sequence.