Proton Pump Inhibitors for EOE

40 to 50 percent of patients are histologic responders to proton pump inhibitors for EOE. PPI trials are okay when you're dealing with someone who's presenting with heartburn, regurgitation, reflux symptoms and no weight loss. If people have non-cardiac chest pain, I'm like, could this be distal esophageal spasm? And then way down the list is true motility disorder, distillisophagealspasms.