Is Ketamine a Dissociative Anesthetic?

Ketamine is an NMDA antagonist, the N-methyl-DS-partate. So those channels kind of exist all over the central nervous system but are a little bit more concentrated within the thalamus and the thalamic cortical interaction. That's why they call it a dissociative anesthetic because you're kind of unplugging the thalams. The main ones like propofolotamidate or ketamine act as their GABA receptor to increase inhibitory effect. Whereas Ketamine acts on an excitatory pathway but inhibits it.