With the full reveal of The Mitochondrial Triad coming soon, it begs the question: why do I believe the focal point of our health, wellness, and, more precisely, our longevity is centered around or organelle friends, the mitochondria? And with the first two pillars being disclosed, in red light therapy and methylene blue, what is the third pillar? All of these questions are answered in today's solosode!
For decades, the primary thesis for why we age was The Free Radical Theory of aging. However, this doesn't hold up in instances where someone consistently exercises (and, thus, produces more ATP that inherently produces more of the natural byproduct of free radicals) that leads to health- and longevity-promoting benefits. That's where The Mitochondrial Theory of Aging emerges and is currently the most respected postulation on why we age. However, the first rendition of this theory still included free radicals as a main culprit for aging; this was remedied in the second version, which removed free radicals as the central causation for aging and suggested the main source was in the numerous mechanisms lying within the mitochondria. Ultimately, this is the genesis that fuels the importance of The Mitochondrial Triad.
After a thorough discussion on The Mitochondrial Theory of Aging, I cover the third pillar of The Mitochondrial Triad! I dive into the top 10 health benefits and numerous other health benefits that have been proven out in the research. Disclaimer: I never say the actual name of the third pillar and refer to it in this portion of the episode as, "the thing." Yes, I know... very descriptive. But you didn't think I would actually reveal it yet, did you?! We'll save that for next week's episode...
I hope you enjoy the information in today's solosode. Please share this episode with family, friends and colleagues if you find the content especially interesting and/or impactful.
As always, light up your health!
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Key Points:
Podcast Kickoff (00:00:01 - 00:01:22)
Mitochondrial Triad Focus (00:01:22 - 00:02:30)
Collaboration and New Product (00:02:30 - 00:03:33)
Mitochondrial Importance (00:03:33 - 00:05:15)
Optimizing Mitochondrial Health (00:05:15 - 00:08:15)
Virtuous Cycle and Longevity (00:08:15 - 00:09:49)
Known Pillars and Anticipation (00:09:49 - 00:10:46)
Mitochondrial Theory of Aging (00:10:46 - 00:12:25)
Aging and Mitochondrial Theory (00:15:52 - 00:16:24)
Mitochondrial DNA Changes (00:16:24 - 00:17:35)
Impact of Mutations (00:17:35 - 00:18:40)
Mitochondrial Reactive Oxygen Species (00:18:40 - 00:19:56)
Dual Nature of Reactive Oxygen Species (00:19:56 - 00:21:30)
Mitochondrial Dynamics (00:21:30 - 00:22:38)
Impaired Mitophagy (00:22:38 - 00:23:43)
Mitochondria in Atherogenesis (00:23:43 - 00:25:11)
Somatic Mutations and Atherosclerosis (00:25:11 - 00:26:15)
Book Recommendation (00:26:15 - 00:27:07)
Deep Science Talk (00:27:23 - 00:28:46)
Free Radicals and Mitochondrial Dysfunction (00:28:46 - 00:29:47)
Bioenergetic Mosaic (00:29:47 - 00:30:19)
Misunderstandings About Free Radicals (00:30:19 - 00:31:41)
Mitochondrial Population Flux (00:31:41 - 00:32:49)
Redox State and Transcription Factors (00:32:49 - 00:33:54)
Third Pillar Revelation (00:33:54 - 00:39:32)
User Reports and Mitochondrial Theory (00:39:32 - 00:40:46)
Cosmetic Applications (00:40:46 - 00:41:43)
Cancer Protection and Hair Growth (00:41:43 - 00:42:50)
Scientific Interest and Applications (00:42:50 - 00:45:27)
Excitement and Synergy (00:45:27 - 00:47:06)
Closing Remarks and Next Episode (00:47:06 - 00:48:04)
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Article from episode:
Mitochondrial Aging and Age-Related Dysfunction of Mitochondria
Recommended book on mitochondria:
Mitochondria and the Future of Medicine - Lee Know, MD
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