Freely Filtered 055: STOP ACE!
Freely Filtered, a NephJC Podcast
ACE Inhibition in Heart Failure
The key thing for the people randomizing them into the trial was they needed to have equipoise. And I think we felt there was no equipoise for people with heart failure. So in reality, even though it may have been listed as an exclusion criteria, effectively it was one. If you look at the Consort diagram, there was a huge number of people who were screened who were ineligible. A large proportion of that was down to this GFR criteria because you had to fill in a spreadsheet with all these creatinines. Unless it literally, you know, you got the linear aggression on this line or worse, they didn't get into the, they couldn't be randomized.
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