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Methylate Your Way to Mental Health With Dopamine | Mastering Nutrition #34

Mastering Nutrition

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Dopaminergic Tone and Dopa-Reuptake in SSRIs

When we are exposed to new stimuli that may compete for our attention and motivation, we release a pulse of dopamine. Dopamine comes out into the synapse to carry out some signaling process and then it's very rapidly taken up in a process called reuptake. The phasic pulses of dopamine are not long lasting at all. They're fractions of a second and they're taken up through reuptake  and once they're take up, they're primarily degraded by oxidation through monomine oxidase which is a copper dependent enzyme. So probably variations in monomine oxide activity are going to affect thesephasic pulses but if they do, they're going to affect

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