New/Guidelines: 1-BED and SUP Guidelines
ICU Ed and Todd-Cast
Navigating Sepsis Trial Design
This chapter examines the inclusion criteria and complexities of a sepsis intervention trial focused on adults showing signs of infection. The speakers discuss the implications of defining 'time zero,' the challenges of adhering to strict guidelines, and the need for flexible trial designs. They also critique outcomes related to mortality and antibiotic stewardship amidst ongoing debates about early antibiotic administration in emergency settings.
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