Is CRS and ICANN's an Impediment to Oncology?

CRS and ICANN's is not necessarily an impediment to the therapy but it is just an acknowledgement that that can come. And we just will have systems in place and guidelines in place to bring these therapies to the patients. The CRS was seen with this drug but remember CRS I'm not sure the pathophysiology and the pathobiology of CRS is the same in our by specifics are T cell engages as it is for CAR T cell.