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Paraneoplastic neurological syndromes: a practical approach to diagnosis and management

Practical Neurology Podcast

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Is There a Prevalence of Pleocytosis in CSF?

A few samples tested in a routine testing laboratory for, for example, LGI1 antibodies will be false negatives. And when you see the patient, it can be quite confusing. One of the reasons these patients have reached our attention is because they have been weaned off their immunotherapy early in the context of a falsely reassuring negative result. So I think there are reasons to really think this could directly influence clinical practiceQuite commonly, actually. The CSF findings as one of often the first results that we get back.

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