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Freely Filtered 060: HCTZ v Kidney Stones, The NOSTONE trial

Freely Filtered, a NephJC Podcast

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The Difference Between 25 and 50 Milligram Hydrochlorothiazide

In the placebo group, there was 67 new stones detected in 94 patients. In the 12 and a half milligram group, 45 of 101 in the 25 milligram hydrochlorothiazide group. Of those with new stones, there wasn't a significant difference. But again, when they do a trend analysis, it's not significant because 25 and 50 look very similar.

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