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Why does methylfolate act as the off-switch for the glycine buffer system? | Masterjohn Q&A Files #272

Mastering Nutrition

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The Glycine Buffer System and the Fasting State Dynamic

Methylpholi is seen as a signal of the fasting state low Sammy dynamic. The body doesn't buffer the excess methyl groups if the glycine buffer system is maximally suppressed. So when you have excess methyl groups, that's when the glycinebuffer system turns on. And when you don't have excessmethyl groups, that'm when it turns off.

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