John Ioannidis on Statistical Significance, Economics, and Replication
EconTalk
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How Many Regressions Did You Run?
In economics, there are so many decision nodes to try different things that you can't even count them. In epidemiology and genetics, for example, it's very difficult to estimate the exact multiplicity burden in that case. "We are probably fooling ourselves because we're going down that Garden of Forking Pass," he says.
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