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Advancements in AML Treatment for Fragile Patients
This chapter evaluates the progress in treating acute myeloid leukemia (AML) for patients unfit for intensive therapies, focusing on the use of azacitidine and venetoclax. The discussion highlights significant clinical trials, including Viali-A and LACEWING, demonstrating improved response rates and survival outcomes while addressing the challenges of myelosuppression management. Additionally, the speakers emphasize the importance of trial data in informing treatment strategies and the implications of cost-effectiveness in clinical practice.