#98 – Uncomplicated UTIs: Getting Uncomfortable with Uncertainty
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Optimizing White Blood Cell Thresholds in UTI Diagnosis
This chapter explores the uncertainties surrounding white blood cell thresholds in diagnosing UTIs, discussing studies suggesting a shift in threshold values for urine cultures. It emphasizes the importance of maximizing test specificity in labs and the challenges institutions face in determining their own thresholds. The conversation also delves into successful stewardship interventions and the use of negative predictive value to reduce unnecessary antibiotic prescriptions.
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