As long as vacuum decay is possible, we can't have had little black holes of a certain size produced during the Big Bang. Small ones that would have evaporated by now might have destroyed the universe. But what we can do with smashing particles together at the Large Hadron Collider is way less powerful than what cosmic rays do in space all the time. So there's no prospect of a Doctor Strange Love doomsday device using vacuum decay? No, it doesn't seem possible.

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