How to Transform the Human Condition

5min Snip

00:00

Play full episode

Summary

Transcript

Episode notes

Deep learning can be used to learn cell specific networks across millions of cells. Large language models have also been extremely helpful for structure. In Alzheimer's just a few weeks ago we had a paper in nature looking at APOE4, the strongest genetic association with Alzheimer's. And we showed that it actually leads to a loss of being able to transport cholesterol in myelinating cells known as oligodendrocytes which basically protect the neurons. So all of these circuits are basically now giving us handles to truly transform the human condition. We're doing the same thing in cardiac disorders, in Alzheimer's, in neurodegenerative disorders, in psychiatric disorders.

Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors:
– Eight Sleep: https://www.eightsleep.com/lex to get special savings
– NetSuite: http://netsuite.com/lex to get free product tour
– ExpressVPN: https://expressvpn.com/lexpod to get 3 months free
– InsideTracker: https://insidetracker.com/lex to get 20% off

EPISODE LINKS:
Manolis Website: http://web.mit.edu/manoli/
Manolis Twitter: https://twitter.com/manoliskellis
Manolis YouTube: https://youtube.com/@ManolisKellis1

PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
YouTube Full Episodes: https://youtube.com/lexfridman
YouTube Clips: https://youtube.com/lexclips

SUPPORT & CONNECT:
– Check out the sponsors above, it’s the best way to support this podcast
– Support on Patreon: https://www.patreon.com/lexfridman
– Twitter: https://twitter.com/lexfridman
– Instagram: https://www.instagram.com/lexfridman
– LinkedIn: https://www.linkedin.com/in/lexfridman
– Facebook: https://www.facebook.com/lexfridman
– Medium: https://medium.com/@lexfridman

OUTLINE:
Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) – Introduction
(06:44) – Humans vs AI
(15:50) – Evolution
(37:34) – Nature vs Nurture
(50:03) – AI alignment
(56:27) – Impact of AI on the job market
(1:08:06) – Human gatherings
(1:13:07) – Human-AI relationships
(1:23:11) – Being replaced by AI
(1:35:37) – Fear of death
(1:47:33) – Consciousness
(1:54:58) – AI rights and regulations
(2:00:41) – Halting AI development
(2:13:52) – Education
(2:19:16) – Biology research
(2:26:36) – Meaning of life
(2:29:09) – Loneliness