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How to Avoid Lactose Malabsorption
If you get a GI tract infection, for example, Giardia can cause damage to your small intestine where this enzyme is located. So in theory, you could still produce lactase, but the cells are so damaged that there's no way to produce lactase. In most adult mammals, it is totally normal for the activity of the lactase enzyme to down-regulate as we age. It means that this enzyme works really well when we're babies in infants.