How can scientists leverage AI and machine learning to more effectively research, develop, and deliver new drugs? This week, Reid and Aria talk drug development with renowned computer scientist and executive Dr. Daphne Koller, whose company, insitro, uses machine learning to improve the quality and speed of drug discovery. She addresses several ways AI and ML are already being used to redefine diseases and create better therapeutic interventions. Plus, she shares her experience transitioning from academia to industry.
Read the transcript of this episode here: https://www.possible.fm/podcasts/dkoller
For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Topics:
00:01: Cold open
00:43: Hellos and intros
3:20: Early involvement in AI
5:00: Overview of drug discovery and its evolution over the last five years
7:50: AI and machine learning impact on biology and drug development
9:09: Pi aside defining AlphaFold
11:37: Areas of acceleration and opportunity in AI and drug discovery
17:21: Synthetic data
21:21: AI implications on therapeutic hypotheses
23:54: Personalized vs. precision medicine
27:04: Closing the data feedback loop
30:31: Exciting announcements
34:24: Privacy and data
36:41: GPT-4 story
38:48: Stuart Russell’s comments on the applications of Koller’s thesis
43:36: AI as a moving target
47:24: How can academia and industry positively impact society and humanity
51:58: insitro’s culture
54:18: - Rapid-fire questions
Select mentions:
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Stuart Russell
Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
