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Manesh Girn - Beyond the Default Mode Network: Psychedelics & Complex Systems

The Psychedelic Podcast

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Psychedelics and Neuroplasticity

The affinity of 5 meo for serotonin 1a is somewhere around 300 to a thousand times more so it really goes there and you only get strong serotonin 2a receptor activation at higher doses. This has ramifications for neuroplasticity that we really just don't even know yet because the research is still in its infancy. In terms of how to make a psychedelics more precise i think it's really about one understanding more about where these drugs target, he says.

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