#71 – Saloni Dattani on Malaria Vaccines and Missing Data in Global Health
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The Trials and Errors of Developing a Malaria Vaccine
This chapter discusses the long and iterative process of developing a malaria vaccine, starting in the mid-1980s and achieving a breakthrough composition in 1994. It covers the use of prison volunteers and challenge trials in early research, as well as the ethical concerns surrounding them. The chapter also explores the challenges faced during field trials in the Gambia, including funding difficulties and uncertainties about the long-term effectiveness of the RTSS vaccine.
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