What Causes Alzheimer's? Scientists Are Rethinking the Answer. (Pt 2)
The Quanta Podcast
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The Amyloid Cascade Hypothesis and the Immune System
After so many years of drug failures, the Lecanamab results were welcome news for John Hardy. Hardy helped to launch the amyloid cascade hypothesis decades ago and still believes in its power. In 2013, Hardy discovered that mutations in a gene involved in the immune system could increase the risk of developing late onset Alzheimer's disease.
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