#204 NephMadness 2020: SGLT2 Inhibitors
The Curbsiders Internal Medicine Podcast
Mechanisms of SGLT2 Inhibitor Effects and Benefits
The speakers explore the potential mechanisms of action of SGLT2 inhibitors in inducing various effects and benefits, including reversing inflammatory cytokines and fibrotic mediators, reducing fibrosis in the heart, increasing insulin sensitivity and promoting ketogenesis, blocking inflammation and prothrombosis, and more. They challenge the idea that the benefits solely rely on TGFeg feedback and emphasize the importance of other mechanisms.
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