
Episode 26: Sugammadex with Dr. Amit Prabhakar
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast
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Introduction
Sugamadex is a revolutionary medication that was just approved by the FDA in December of 2015 and indicated for the reversal of both moderate and deep neuromuscular blockade. After IV injection of the medication, the molecule distributes throughout the plasma and binds to neurostigmatic lipopyrite. Of note though, this does not affect the release or breakdown of acetylcholine. So we think of normally what we do with our neostigmatin as we are blocking the breakdown ofacetylcholine,. In this case, you're saying this drug surrounds and encapsulates the rockeronium and therefore it can't act at all. Exactly.
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