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The Naked Scientists Podcast
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How to Reprogramme White Blood Cells to Target Leukemia Cells
In recent years, doctors have begun to treat cancers of the blood called leukemias by reprogramming some of a patient's own white blood cells. This is called CAR-T cell therapy, and it's very effective. The problem is that it's also very expensive because it has to be done on an individual patient basis. Much more effective would be to engineer cells in advance that anyone could use. And this week, researchers at the Institute of Child Health in Great Ormond Street, London, have announced that they've done just that. They've edited the DNA of donor white blood cells to disarm and cloak them so they don't attack healthy tissue or get taken down by a
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