Using AI to Discover Small Molecule Alternatives to Biologics
The Bio Report
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Innovative Drug Discovery Through AI and Collaboration
This chapter explores the development of small molecule alternatives to biologics, emphasizing the role of AI and human expertise in the drug discovery process. It discusses the creation of a selective BRD4 inhibitor and a STAT6 inhibitor, highlighting their efficacy in treating autoimmune diseases while minimizing toxic effects. The integration of automated platforms is showcased as a means to reduce delays in testing and optimize lead candidates, transforming previously undruggable targets into viable therapeutic options.
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