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#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

The Peter Attia Drive

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Is There a Mechanism by Which Met Foreman Reduces Inflammation?

There's going to be another trial announced very soon that i think will show similar results using lodo mestrexe. So we think that reactive oxygen species is the free radicals can serve as signaling molecules to activate cidokins. And met for men by inhibiting the respiratory chain, which is the major side of those reactive oxygen species and decreases citokin in production. It's a weak inhibitor of the respirtory chan; if you knock out the respiritory chain completely, you can't never turn on this.

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