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Studying a shark-haunted island, and upgrading our microbiomes with engineered bacteria

Science Magazine Podcast

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Engineering Gut Health: Bacteria and Kidney Stones

This chapter examines the role of gut microbiota in human health and its potential for therapeutic interventions, particularly in the context of kidney stones. It discusses the engineering of bacteria to address oxalate absorption and the innovative approaches involving dietary prebiotics to enhance their effectiveness. Clinical trials reveal insights into the performance of these engineered strains in healthy individuals and patients with high oxalate levels, highlighting both success and challenges in their implementation.

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