This chapter discusses the potential of cancer vaccines, challenges in developing effective treatments, and features a promising phase one trial for pancreatic cancer. It also delves into advancements in gene editing technologies like CRISPR, the race to solve delivery issues in gene therapy, and ethical concerns around gene editing. Additionally, the chapter explores the role of AI in cancer research, its impact on diagnostics and drug discovery, and the complexities of finding the right treatment for cancer patients.
In high school, Reed Jobs was a summer intern in oncology labs while his dad, the late Apple co-founder and tech icon Steve Jobs, was battling pancreatic cancer. In his biography, Steve is quoted as calling his son’s interest in biotech the “silver lining” of his illness – and making cancer “non-lethal” has become Reed’s life mission. In 2023, he spun off the venture capital firm Yosemite from Emerson Collective (the philanthropy and family office founded by his mother, Laurene Powell Jobs) to focus on cancer research and biotech. Kara and Reed talk about the research-to-start up pipeline, how he’s been influenced by both of his parents, and whether AI, mRNA or CRISPR will be game changers for cancer patients.
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