Therapy Effectiveness, Pricing Pressures, and Biosimilar Challenges

On this week’s Biotech Hangout, hosts Brad Loncar, Daphne Zohar, Bruce Booth, Josh Schimmer and Yaron Werber cover the state of the XBI after it hit a 52-week low. They also discuss several deals and financings from the week including Eli Lilly acquiring Point Biopharma ($1.4B) and radiopharma more generally and Sanofi paying Teva to collaborate on inflammatory bowel disease treatment (up to $1.5B). Also Biohaven’s offering (~$225M), Amicus Therapeutics’ financing with Blackstone ($430M), and Orchard Therapeutics acquired by Kyowa Kirin ($478M).  Takeda announces withdrawal of EXKIVITY after its accelerated approval gets pulled, Syndax, ALX Oncology and Roche data and Boehringer Ingelheim launches biosimilar to AbbVie’s Humira at an 81% discount. Other topics include Amgen’s KRAS inhibitor under FDA review, Exscientia and AI, Ionis Pharmaceuticals’ R&D day and Infinity Pharmaceuticals shuts down. *This episode aired on October 6, 2023