How to Reverse Heparin With Proton Mean

Proton mean is typically what we use to reverse heparin It is a cation that binds heparin and causes basically forms assault and and renders heparin inactive. We give this very slowly there are four main reactions that can happen with proton mean the first that we see the most common Is it causes a histamine release mass cell degranulation they get hypotensive So we typically give proton mean peripherally and very slowly over about five to ten minutes Um, it can also cause an anaphylaxis reaction or anAnaphylactoid type reaction And then the last one which can be the most catastrophic is it can cause very severe pulmonary hypertension and therefore right heart