The Promise of Predictive Modeling in Clinical Healthcare

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In episode 45 of The Gradient Podcast, Daniel Bashir speaks to Zachary Lipton.

Zachary is an Assistant Professor of Machine Learning and Operations Research at Carnegie Mellon University, where he directs the Approximately Correct Machine Intelligence Lab. He holds a joint appointment between CMU’s ML Department and Tepper School of Business, and holds courtesy appointments at the Heinz School of Public Policy and the Software and Societal Systems Department. His research spans core ML methods and theory, applications in healthcare and natural language processing, and critical concerns about algorithms and their impacts.

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Outline:

* (00:00) Intro

* (2:30) From jazz music to AI

* (4:40) “fix it in post” we had some technical issues :)

* (4:50) spicy takes, music and tech

* (7:30) Zack’s plan to get into grad school

* (9:45) selection bias in who gets faculty positions

* (12:20) The slow development of Zack’s wide range of research interests, Zack’s strengths coming into ML research

* (22:00) How Zack got attention early in his PhD

* (27:00) Should PhD students meander?

* (30:30) Faults in the QA model literature

* (35:00) Troubling Trends, antecedents in other fields

* (39:40) Pretraining LMs on nonsense words, new paper!

* The new paper (9/29)

* (47:25) what “BERT learns linguistic structure” misses

* (56:00) making causal claims in ML

* (1:05:40) domain-adversarial networks don’t solve distribution shift, underspecified problems

* (1:09:10) the benefits of floating between communities

* (1:14:30) advice on finding inspiration and learning

* (1:16:00) “fairness” and ML solutionism

* (1:21:10) epistemic questions, how we make determinations of fairness

* (1:29:00) Zack’s drives and motivations

Links:

* Zachary’s Homepage

* Papers

* DL Foundations, Distribution Shift, Generalization

* Does Pretraining for Summarization Require Knowledge Transfer?

* How Much Reading Does Reading Comprehension Require?

* Learning Robust Global Representations by Penalizing Local Predictive Power

* Detecting and Correcting for Label Shift with Black Box Predictors

* RATT

* Explanation/Interpretability/Fairness

* The Mythos of Model Interpretability

* Evaluating Explanations

* Does mitigating ML’s impact disparity require treatment disparity?

* Algorithmic Fairness from a Non-ideal Perspective

* Broader perspectives/critiques

* Troubling Trends in Machine Learning Scholarship

* When Curation Becomes Creation