TDM1 - Is There a Signal?

The international trial of TDM1 wasn't that impressive, but maybe a signal in these amplified cases with TDM1. And then our investigator sponsored trial at Memorial Sloan Kettering, it's a cohort in the basket trial ofTDM1, which I had led. So we had a 44% response rate, we had a median progression free survival of five months. This was in heavily pre-treated patient populations, often third, fourth, fifth line of therapy with prior chemo,. Prior her two targeted therapy, and prior I.O. so they really had nothing left to give except chemotherapy like Veneralbi or something.