This chapter delves into the concept of information in biology, discussing genome length, redundancy, and the relationship between fitness and information. It examines the challenges of measuring information content in DNA, the significance of non-coding regions like long non-coding RNAs, and the role of RNA molecules in cellular biology. The chapter also explores the origin of life, the RNA world hypothesis, and the complexity of information replication in biological systems.
Evolution is sometimes described -- not precisely, but with some justification -- as being about the "survival of the fittest." But that idea doesn't work unless there is some way for one generation to pass down information about how best to survive. We now know that such information is passed down in a variety of ways: through our inherited genome, through epigenetic factors, and of course through cultural transmission. Chris Adami suggests that we update Dobzhansky's maxim "Nothing in biology makes sense except in the light of evolution" to "... except in the light of information." We talk about information theory as a subject in its own right, and how it helps us to understand organisms, evolution, and the origin of life.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/02/19/266-christoph-adami-on-how-information-makes-sense-of-biology/
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Christoph Adami received his Ph.D. in physics from Stony Brook University. He is currently professor of Microbiology and Molecular Genetics as well as Physics and Astronomy at Michigan State University. Among his awards are the NASA Exceptional Achievement Medal and the Lifetime Achievement Award from the International Society for Artificial Life. His new book is The Evolution of Biological Information: How Evolution Creates Complexity, from Viruses to Brains.
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