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June 2 This Week in Cardiology

This Week in Cardiology

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The Dangers of Making Causal Conclusions From Non-Randomized Data

John Mandrola: Non-random association studies are always susceptible to selection bias. Dr. Anil Mokham a super smart academic intern has pushed back on my caution by saying there's no clinical exploits here or expectation that bringing the number down will change any of these outcomes for non-cardia hospitalizations. He said this is more of a one-side analysis of the harms of an errant practice. Proponents of anything aggressive bear the burden of proof.

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