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Episode 19 - DIC

The Curious Clinicians

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The Effects of Heparin on Cardiovascular Outcomes

Hannah, would it be fair to say that in some ways DIC is causing many thousands of small pulmonary emboli and so leading to the same kind of physiology that you see when you have one large pulmonary embolism? I'm not going to put words in your mouth, but that's what it sounded like. That's essentially the concept that would be suggested by the fact that the phenoxybenzamine was able to prevent some of the like hemodinamic collapse that was associated with inducing DIC or with DIC. The whole issue is that whatever is causing the DIC itself will most likely also cause hypotension. And so there's probably a whole lot of different

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