Time of day could affect how breast cancer spreads. Researchers found that circulating tumour cells release depending on the mouse's circadian rhythm. Metastasis is generally associated with worse clinical outcomes for cancer patients. But although it is such an important aspect of cancer, it is still poorly understood why they are released in the first place.
00:38 The science of studying inequality
We discuss the research looking to understand the root causes and symptoms of inequalities, how they are growing, and how a cross-disciplinary approach may be the key to tackling them.
07:26 The randomised trials helping to alleviate poverty
For decades, researchers have been running randomised trials to assess different strategies to lift people out of poverty. Many of these trials centre on providing people with cash grants – we hear how these trials have fared, efforts to improve on them, and the difficulties of scaling them up.
21:23 Why breast cancers metastasize differently at different times of day
A team of researchers have found that breast cancer tumours are more likely to metastasize while people are asleep. By studying mice, the team suggest that hormone levels that fluctuate during the day play a key role, a finding they hope will change how cancer is monitored and treated.
A comment article in Nature argues that one of the most pernicious types of inequality is inequality of opportunity – based on characteristics over which people have no control. We discuss some of the data behind this and what can be done about it.