Lenalidomide and genetic profiling in myeloma, T-cell immunotherapy upregulates AML cell MHC-class II, and young fecal microbiota rejuvenate HSCs
Blood Podcast
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The Role of Gut Microbiota in Hematopoiesis
Fecal Microbiota Transplantation from Young Mice Rejuvenates Aged Hematopoietic Stem Cells By Suppressing Inflammation. Using interferon gamma by specific molecules, CAR T-cells and other immunotherapies is a potential strategy to treat patients in post-transplant AML relapse. Doing so may also rejuvenate the graft versus tumor effect by reversing down regulation of MHC2 on AML blasts.
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